What is Sarcomatoid Mesothelioma. Symptoms and Treatment.


Sarcomatoid mesothelioma is the least common of the cell types. Sarcomatoid cells metastasize faster than other mesothelioma cell types, causing the formation of cancerous tumors in other areas of the body. This makes sarcomatoid the most dangerous cell type, most aggressive and the most difficult to treat. Sarcomatoid mesothelioma is very difficult to diagnose, and a lot of patients are misdiagnosed at the early stage. In addition to being very rare, sarcomatoid mesothelioma cells can look like healthy tissue. Making it even more difficult to determine whether they are malignant. Sarcomatoid mesothelioma occurs between 10 and 20% of patients with mesothelioma. Sarcomatoid The most lethal histological type of mesothelioma, in terms of life expectancy, is sarcomatoid.

Diagnosing the Sarcomatoid Mesothelioma

With all forms of cancer, early diagnosing is very important to provide a patient with the best opportunities for treatment and long-term survival. Sarcomatoid mesothelioma is no exception but due to the long latency period before symptoms emerge and its aggressive nature, it is difficult to diagnose at an early stage.Sarcomatoid Mesothelioma

The diagnosis of mesothelioma can occur in many ways. Diagnosing this cell type is difficult because these tumors tend to mimic other benign and malignant conditions in appearance. When pathologists examine these tissue samples under a microscope, the cells resemble those of sarcoma tumors and localized fibrous tumors of the pleura. Though asbestos is the only proven cause of malignant mesothelioma. There are other suspected risk factors that may make a patient more susceptible to developing the disease.

Treatment of Sarcomatoid

Treatment usually involves combining chemotherapy, surgery, and radiation. Since the diagnosis of mesothelioma usually occurs in phase III or later, the goal of treatment will usually focus on prolonging patient survival and improving their quality of life. The incidence rate of mesothelioma in the USA is around 0.97 per 100,000 between 1973 and 1999. Between 2,000 and 3,000 new cases are discovered each year.

Symptoms of Sarcomatoid Mesothelioma

Symptoms of this Sarcomatoid type of cancer are similar to the symptoms of other mesothelioma cell types. The symptoms that patients initially present may include:

Common Symptoms of Sarcomatoid Mesothelioma
  • Abdominal pain
  • Chest pain
  • Cough
  • Difficulty breathing
  • Fatigue
  • Fever
  • Loss of appetite
  • Nausea
  • Shortness of breath
  • Weight loss

Life Expectancy in Sarcomatoid Mesothelioma

Next to epithelioid mesothelioma and biphasic mesothelioma, the sarcomatoid type has the worst prognosis due to its aggressive nature and poor response to treatment. Even with quick treatment at the first sight of symptoms, the average survival for sarcomatoid patients is only around 1 year or less.

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